CSSD Practice Exam 2025 – Complete Study Resource

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What effect does testosterone have on bone mass?

It decreases bone density

It has no effect on bone mass

It stimulates osteoclasts

Testosterone plays a significant role in bone health, particularly in stimulating osteoblasts, the cells responsible for bone formation, rather than osteoclasts, which are involved in bone resorption. The correct understanding of testosterone’s effects on bone mass is that it actually promotes the activity of osteoblasts, leading to an increase in bone density and overall bone mass. High levels of testosterone are linked to an increase in bone density and a reduced risk of osteoporosis, especially in males.

The choice regarding testosterone stimulating osteoclasts is incorrect because if anything, testosterone has a suppressive effect on osteoclasts, which are responsible for breaking down bone tissue. Therefore, the relationship between testosterone and bone mass is one of promotion rather than stimulation of resorption. This important distinction highlights the hormone's role in maintaining strong and healthy bones rather than diminishing them.

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It reduces calcium absorption

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